期刊论文详细信息
Eurasian Journal of Analytical Chemistry
Comparing Clinical Responses to Using One Burr Hole and Two Burr Holes to Treat Chronic Subdural Hematoma
关键词: chronic subdural hematoma;    burr hole;    treatment;   
DOI  :  10.29333/ejac/85017
学科分类:分析化学
来源: Eurasian Journal of Analytical Chemistry
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【 摘 要 】

The therapeutic strategies currently used to treat chronic subdural hematoma (CSDH) include various methods such as craniotomy and twist drill or utilizing Burr hole. The present research seeks to make a clinical comparison between using one burr hole and two burr holes to treat CSDH. This is a randomized, double-blind clinical trial conducted on 70 patients suffering from CSDH candidated for using burr hole. The participants were divided into two equal groups and underwent treatment with 1 burr hole or 2 burr holes. The primary and secondary outcome variables were compared across the two groups prior to and 48 hours following the operation. A total number of 5 death cases were (7.14%) were reported among patients. 2 patients (5.71%) were in the 1 burr hole group, while 3 (8.57%) were in the 2 burr hole group (P = 0.514). The need for undergoing a secondary operation in the 2 burr holes group (1 case, i.e. 2.85%) was significantly less than what was reported in the other group (6 cases, i.e. 17.14%) (P = 0.012). The mean time of hospitalization (1 burr hole: 4.98, 2 burr holes: 3.1, P = 0.001), the pneumosephalus levels 48 hours following the operation (1 burr hole: 9.38, 2 burr holes: 5.91, P = 0.012) and hematoma levels 48 hours following the operation (1 burr hole: 41.57, 2 burr holes: 30.85, P = 0.0001) in the 2 burr holes group were significantly less than what were reported in the other group. 48 hours after the operation, the hematoma volume (1 burr hole: P= 0.031, 2 burr holes: P= 0.002) in both groups exhibited a significant reduction compared to what was observed before the operation. Using 1 or 2 burr holes are quite useful methods to treat CSDH patients. However, the clinical outcome of those patients in the 2 burr holes group was much more favorable.

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