Does leptin predict successful induction of labor?

Proceedings in Obstetrics and Gynecology

Brenda Boese¹  Noelle C. Bowdler¹  Donna A. Santillan¹  Wendy Hamilton¹  Mark K. Santillan¹  Sabrina Scroggins¹  Whitney Cowman¹ 

[1] Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa

关键词: Obesity;    induction of labor;    leptin;   

学科分类：妇产科学

来源: University of Iowa

【 摘 要 】

Obesity in pregnancy is becoming increasingly common and is associated with many pregnancy-related complications such as failed induction of labor (IOL). Leptin, an adipocytokine important in energy homeostasis, is found in higher levels in obese individuals. Leptin has also been demonstrated to have an inhibitory effect on myometrial contractility in vitro. We hypothesize that leptin may play a part in the mechanism of dysfunctional labor. Thus, we sought to compare the maternal plasma leptin levels in women that had a successful vaginal delivery post-IOL vs. those who had a C-section post-IOL.

【 授权许可】

Unknown