Probiotics and Their Immunomodulatory Potential

Current Health Sciences Journal

Liana Viau-Bolocan ; Florica Popescu ; Catalina Bica

关键词: probiotic;    intestinal microflora;    immune modulation;    inflammation;   

学科分类：医学（综合）

来源: Universitatea de Medicina si Farmacie din Craiova / University of Medicine and Pharmacy

【 摘 要 】

The definition of probiotics has evolved from a live active culture which improves the balance of the gut microbiota composition to specific effects, in particular, the immunomodulatory potential of clearly defined strains. The strains with beneficial properties, potential sources of probiotics, most frequently belong to the genera Bifidobacterium and Lactobacillus, and some of these strains exhibit powerful anti-inflammatory properties. These effects are attributed to the normal restoration of increased intestinal permeability and unbalanced gut microbiota, improvement of the intestines immunological barrier functions and alleviation of the intestinal inflammatory response. The application of probiotics in pediatric practice currently lies in enhancing these barrier functions in the gut and reducing the risk of diseases associated with their dysfunction. The most fully documented probiotic intervention is the treatment and prevention of acute infectious diarrhea.

【 授权许可】

Unknown