期刊论文详细信息
| Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
| Tissue‐specific NK cell populations and their origin | |
| 关键词: natural killer cell progenitors; hematopoietic progenitors; innate immunity; lymphoid cells; | |
| DOI : 10.1189/jlb.1RU0514-241R | |
| 学科分类:生理学 | |
| 来源: Federation of American Societies for Experimental Biology | |
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【 摘 要 】
Tissue‐specificNKcellsubpopulationsarefoundinadultgut,liver,andendometrium,aswellasothersitesinthebody.SomedifferphenotypicallyandfunctionallyfrompbNKcells,andtheiroriginisdisputed.Inthisreview,wediscusstissue‐specificNKcellsandsuggestthatsubpopulationsdifferentiateinsitufromtissue‐residenthematopoieticprogenitorcells.Theunderstandingoftheoriginsandmaturationrequirementsoftissue‐specificNKcellscouldleadtonewclassesofimmunotherapyfororgan‐specificpathologiesofinfectiousandmalignantorigin...
【 授权许可】
CC BY
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201904046986968ZK.pdf | 437KB |
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