期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
The role of type 2 innate lymphoid cells in asthma | |
关键词: airway hyper‐; reactivity; NKT cells; allergy; influenza; | |
DOI : 10.1189/jlb.0313127 | |
学科分类:生理学 | |
来源: Federation of American Societies for Experimental Biology | |
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【 摘 要 】
Asthmaisacomplexandheterogeneousdiseasewithseveralphenotypes,includinganallergicasthmaphenotype,characterizedbyTh2cytokineproductionandassociatedwithallergensensitizationandadaptiveimmunity.Asthmaalsoincludesnonallergicasthmaphenotypesthatrequireinnateratherthanadaptiveimmunity.Theseinnatepathwaystoasthmainvolvemacrophages,neutrophils,aswellasILCs,newlydescribedcelltypesthatproduceavarietyofcytokines,includingIL‐5andIL‐13.WereviewtherecentdataregardingILCsandtheirroleinasthma...【 授权许可】
CC BY
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