期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society
The role of type 2 innate lymphoid cells in asthma
关键词: airway hyper‐;    reactivity;    NKT cells;    allergy;    influenza;   
DOI  :  10.1189/jlb.0313127
学科分类:生理学
来源: Federation of American Societies for Experimental Biology
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【 摘 要 】
Asthmaisacomplexandheterogeneousdiseasewithseveralphenotypes,includinganallergicasthmaphenotype,characterizedbyTh2cytokineproductionandassociatedwithallergensensitizationandadaptiveimmunity.Asthmaalsoincludesnonallergicasthmaphenotypesthatrequireinnateratherthanadaptiveimmunity.Theseinnatepathwaystoasthmainvolvemacrophages,neutrophils,aswellasILCs,newlydescribedcelltypesthatproduceavarietyofcytokines,includingIL‐5andIL‐13.WereviewtherecentdataregardingILCsandtheirroleinasthma...
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