Crystal structure of (1S,3R,8R,10S)-2,2-di­chloro-10-hy­droxy-3,7,7,10-tetra­methyl­tri­cyclo­[6.4.0.01,3]dodecan-9-one

Acta Crystallographica Section E: Crystallographic Communications

Abdelwahed, A.¹  Benzalim, A.³  Auhmani, A.⁴  Daran, J.-C.⁵  Ait Itto, M.Y.⁶ 

[1] des Sciences, Semlalia BP 2390, Marrakech 40001, Morocco;Laboratoire de Chimie de Coordination, CNRS UPR8241, 205 route de Narbonne, 31077 Toulouse Cedex 04, France;Laboratoire de Physico-Chimie Moléculaire et Synthèpartement de Chimie, Facultése Organique, Dé

关键词: CRYSTAL STRUCTURE;    [ALPHA]-HYDROXYKETONE;    ASYMMETRIC SYNTHESIS;    NATURAL PRODUCTS;    ABSOLUTE CONFIGURATION;    HYDROGEN BONDING;   

DOI  :  10.1107/S2056989016006174

学科分类：数学（综合）

来源: International Union of Crystallography

【 摘 要 】

The asymmetric unit of the title compound, C16H24Cl2O2, contains two independent mol­ecules (A and B) which are built from three fused rings, viz. a seven-membered heptane ring, a six-membered cyclo­hexyl ring bearing a ketone and an alcohol group, and a cyclo­propane ring bearing two Cl atoms. In the crystal, the two mol­ecules are linked via two O—H⋯O hydrogen bonds, forming an A–B dimer with an R22(10) ring motif. The A mol­ecules of these dimers are linked via a C—H⋯O hydrogen bond, forming chains propagating along the a-axis direction. Both mol­ecules have the same absolute configuration, i.e. 1S,3R,8R,10S, which is based on the synthetic pathway and further confirmed by resonant scattering [Flack parameter = 0.03 (5)].

【 授权许可】

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