Turkish Journal of Biology | |
Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss. | |
SİNEM ÖZKAYNAK1  | |
关键词: Anthemis aciphylla; anti-inflammatory activity; carrageenin; paw edema; cotton pellet; | |
学科分类:生物科学(综合) | |
来源: Scientific and Technical Research Council of Turkey - TUBITAK | |
【 摘 要 】
Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
【 授权许可】
Unknown
【 预 览 】
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RO201904038438729ZK.pdf | 97KB | download |