A simple and green procedure for the synthesis of 5-arylidene-4-thiazolidinones by grinding

Green Chemistry Letters and Reviews

Nadia H. Metwally¹ 

关键词: 5-arylidene-4-thiazolidinones;    4-thiazolidinediones;    aromatic aldehydes;    anhydrous ammonium acetate;    solvent-free synthesis;    grinding;   

DOI  :  10.1080/17518253.2010.544330

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

An improved green Knoevenagel condensation of various aromatic aldehydes with 4-thiazolidinones in the presence of anhydrous ammonium acetate can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions.

【 授权许可】

Unknown