期刊论文详细信息
| American Journal of Clinical and Experimental Urology | |
| Mini-review: Does Notch promote or suppress cancer? New findings and old controversies | |
| Irina B Grishina1 | |
| 关键词: Notch; cancer; PTEN; Wnt; | |
| DOI : | |
| 学科分类：医学（综合） | |
| 来源: e-Century Publishing Corporation | |
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【 摘 要 】
Notch signaling in tumorigenesis and cancer progression presents a certain enigma. Numerous experimental studies reported significant effects in cancer, yet of varying magnitude and opposite sign. This mini review is aimed to streamline our understanding of the Notch role in tumor progression, and outline future experiments to clarify the modality of Notch function and perspectives of the Notch-based anticancer treatments.
【 授权许可】
CC BY-NC
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201904035827792ZK.pdf | 207KB |  download |
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