Bioassay studies of 2'-O-ethylmurrangatin isolated from a medicinal plant, Murraya paniculata

Turkish Journal of Biology

AZIZUDDIN SHAIKH¹ 

关键词: Murraya paniculata;    Rutaceae;    2^'-O-ethylmurrangatin;    antioxidant;    DPPH radical scavenging assay;    lipoxygenase inhibition assay;    prolyl endopeptidase inhibition assay;    respiratory burst inhibitory assay;   

学科分类：生物科学（综合）

来源: Scientific and Technical Research Council of Turkey - TUBITAK

【 摘 要 】

A secondary metabolite, 2^'-O-ethylmurrangatin (1), was isolated from the leaves of a medicinal plant, Murraya paniculata. The structure of compound 1 was identified with the help of spectroscopic techniques. Compound 1 was screened for its antioxidant, lipoxygenase, prolyl endopeptidase, and respiratory burst inhibitory activities. 2^'-O-Ethylmurrangatin (1) was found to have significant activity against lipoxygenase enzyme and moderate respiratory burst inhibitory activity, but no activity against either DPPH radical scavenging assay or prolyl endopeptidase enzyme.

【 授权许可】

Unknown