期刊论文详细信息
Acta Crystallographica Section E: Crystallographic Communications | |
Crystal structure of (±)-(4RS,5RS,7SR)-4-[(1RS,2RS,3RS,6RS)-3-benzoyloxy-2-(2-hydroxyethyl)-6-methoxymethoxy-2-methylcyclohexyl]-8,10,10-trimethyl-2-oxo-1,3-dioxaspiro[4.5]dec-8-en-7-yl benzoate benzene monosolvate | |
Yamaguchi, Y.1  Chida, N.1  Sugai, T.1  Watanabe, A.1  Sato, T.1  Fukaya, K.1  Oishi, T.2  | |
[1] Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan;School of Medicine, Keio University, Hiyoshi 4-1-1, Kohoku-ku, Yokohama 223-8521, Japan | |
关键词: CRYSTAL STRUCTURE; HYDROGEN BONDS; TAXANE SKELETON; PACLITAXEL; | |
DOI : 10.1107/S2056989014026048 | |
学科分类:数学(综合) | |
来源: International Union of Crystallography | |
【 摘 要 】
In the title compound, C36H44O10·C6H6, the dioxolane ring adopts an envelope conformation with the C atom bonded to the H atom as the flap, while the cyclohexene and cyclohexane rings are in half-chair and chair conformations, respectively. In the crystal, a pair of O—H⋯O hydrogen bonds with an R22(26) graph-set motif connect the benzoate molecules into an inversion dimer. The dimers are linked by a weak C—H⋯O interaction into a tape structure along [01-1]. The benzene molecule links the tapes through C—H⋯O and C—H⋯π interactions, forming a sheet parallel to (100).
【 授权许可】
CC BY
【 预 览 】
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