Development of Exact Matrix‐Matching Inductively Coupled Plasma‐Optical Emission Spectroscopy for the Analysis of Cu and K in Infant Formula

Bulletin of the Korean Chemical Society

Ji Lee¹  Ye‐²  Youngran Lim³  Myung‐³  Hyeon Yim³  Sub Han⁴  Yong‐⁴  Sung Woo Heo⁴ 

[1] Analytical Science University of Science and Technology(UST) Daejeon 217 Gajeong‐Bio‐Center for Inorganic Analytical Chemistry, Metrology for Quality of Life Korea Research Institute of Standards and Science(KRISS) Daejeon 267 Gajeong‐ro Republic of Korea

关键词: Inductively coupled plasma‐;    optical emission spectrometry;    Exact matrix matching;    Isotope dilution inductively coupled plasma‐;    mass spectrometry;    Infant formula;    Copper;    Potassium;   

DOI  :  10.1002/bkcs.10843

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

In the present study, we have developed an exact matrix‐matching inductively coupled plasma‐optical emission spectroscopy (ICP‐OES) as a low‐cost alternative to the isotope dilution inductively coupled plasma‐mass spectrometry (ICP‐MS) method for accurate and precise measurements of nutrient elements K and Cu in infant formula. In spite of its high precision and accuracy, ICP‐OES analysis of complex samples was not reliable due to biases originating from various matrix effects. The elaborated exact matrix‐matching approach tested here demonstrated its potential to minimize biases due to matrix mismatch. The exact matrix‐matching ICP‐OES method was successfully validated by comparing the results with those from an isotope dilution ICP‐MS method. Because the model provides reliable results without significant loss of precision, it will be an excellent choice for major element analysis in a complex sample, especially when isotope dilution is not applicable due to the lack of alternative isotopes or the high cost of enriched isotopes.

【 授权许可】

Unknown