Synthesis of 3-amino 1H-pyrazoles catalyzed by p-toluene sulphonic acid using polyethylene glycol-400 as an efficient and recyclable reaction medium

Green Chemistry Letters and Reviews

N. Suryakiran¹ 

关键词: Polyethylene glycol-400;    p-toluene sulphonic acid;    β-keto nitriles;    hydrazines;    3-amino 1H-pyrazoles;   

DOI  :  10.1080/17518250701771909

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

An efficient synthesis of 3-amino 1H-pyrazoles is described. The reaction of β-keto nitriles with hydrazines in the presence of a catalytic amount of p-toluene sulphonic acid using polyethylene glycol-400 as an efficient and recyclable reaction medium afforded the corresponding 3-amino 1H pyrazoles excellent yields.

【 授权许可】

Unknown