Catalyst-free and solvent-free synthesis of novel symmetrical bisthioglycolic acid derivatives

Green Chemistry Letters and Reviews

Baharak Pooladian¹ 

关键词: thioglycolic acid;    catalyst-free;    solvent-free;    thioethers;    aldehydes;   

DOI  :  10.1080/17518253.2014.895861

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

A simple, efficient, eco-friendly, and cost-effective method has been developed for the synthesis of symmetrical bisthioglycolic acid derivatives by a one-pot reaction of aldehydes or ketones with thioglycolic acid under solvent- and catalyst-free conditions in excellent yields (87–97%). The advantages of this novel protocol include the excellent yields, operational simplicity, short reaction times, and the avoidance of the use of organic solvents and catalysts.

【 授权许可】

Unknown