Cardiac autonomic control in the obstructive sleep apnea

Libyan journal of medicine

Nouha Gammoudi¹ 

关键词: autonomic nervous system;    sleep apnea;    heart rate;    sleep;    circadian;   

DOI  :  10.3402/ljm.v10.26989

学科分类：医学（综合）

来源: Co-Action Publishing

【 摘 要 】

IntroductionThe sympathetic activation is considered to be the main mechanism involved in the development of cardiovascular diseases in obstructive sleep apnea (OSA). The heart rate variability (HRV) analysis represents a non-invasive tool allowing the study of the autonomic nervous system. The impairment of HRV parameters in OSA has been documented. However, only a few studies tackled the dynamics of the autonomic nervous system during sleep in patients having OSA.AimsTo analyze the HRV over sleep stages and across sleep periods in order to clarify the impact of OSA on cardiac autonomic modulation. The second objective is to examine the nocturnal HRV of OSA patients to find out which HRV parameter is the best to reflect the symptoms severity.MethodsThe study was retrospective. We have included 30 patients undergoing overnight polysomnography. Subjects were categorized into two groups according to apnea–hypopnea index (AHI) mild-to-moderate OSAS group (AHI 5–30) and severe OSAS group (AHI>30). The HRV m...

【 授权许可】

CC BY