Crystal structure of ethyl 4-(2-fluoro­phen­yl)-6-methyl-2-sulfanyl­idene-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

Acta Crystallographica Section E: Crystallographic Communications

Krishnamurthy, M.S.¹  Begum, N.S.¹ 

[1]Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560 001, Karnataka, India

关键词: CRYSTAL STRUCTURE;    ESTER;    PYRIMIDINE;    HYDROGEN BONDING;    3,4-DIHYDROPYRIMIDIN-2(1H)-ONE;    THERAPEUTIC PROPERTIES;    PHARMACOLOGICAL PROPERTIES;   

DOI  :  10.1107/S2056989015015145

学科分类：数学（综合）

来源: International Union of Crystallography

【 摘 要 】

The title compound, C14H15FN2O2S, crystallizes with two mol­ecules in the asymmetric unit. In each mol­ecule, the pyrimidine ring adopts a sofa conformation with the sp3-hybridized C atom forming the flap and the fluoro-substituted ring in an axial position. In the crystal, mol­ecules are linked via N—H⋯S hydrogen bonds, forming chains of R22(8) rings along [100]. In one independent mol­ecule, an intra­molecular C—H⋯O hydrogen bond is observed.

【 授权许可】

CC BY