Melatonin Implants Have No Effect on the Testis Volume and Body Weight in Mongolian Gerbils

Turkish Journal of Biology

ALPER KARAKA޹ 

关键词: Implantation;    Melatonin;    Pinealectomy;    Gerbil;   

学科分类：生物科学（综合）

来源: Scientific and Technical Research Council of Turkey - TUBITAK

【 摘 要 】

Photoperiod is an important environmental cue in the regulation of reproductive activity in Mongolian gerbils. Photoperiodic information is ultimately transduced into a hormonal signal by the pineal gland. We examined the effect of constant-release melatonin capsules on the testicular size and body weights of male Mongolian gerbils exposed to a long (14L: 10D) photoperiod. Three groups were formed:control (n = 10), intact + melatonin implant (n = 10) and pinealectomy + melatonin implant (n = 10). The testes and body weights of the gerbils were recorded every week for 8 weeks. Body weights (76 ± 2.0 g intact + melatonin implant; 79 ± 3.0 g pinealectomy + melatonin implant) and testes weights (1.54 ± 0.21 g intact + melatonin implant; 1.47 ± 0.19 g pinealectomy + melatonin implant) of intact + melatonin implanted and pinealectomy + melatonin implanted groups were not statistically different from those of the control group (80 ± 3.1 g body weight; 1.55 ± 0.20 g testes weight) (P > 0.05) at the end of the study. Regardless of treatment, the animals fully reflected the characteristics of a long photoperiod. These results indicate that masking the endogenous melatonin rhythm via constant-release melatonin implants has no effect on the testis volume or body weight of Mongolian gerbils when the animals are kept in a long photoperiod.

【 授权许可】

Unknown