One-pot multicomponent synthesis of polyhydroquinolines under catalyst and solvent-free conditions

Green Chemistry Letters and Reviews

Sudarshan Das¹ 

关键词: Hantzsch condensation;    polyhydroquinolines;    microwave;    catalyst and solvent-free;    four-component;   

DOI  :  10.1080/17518253.2011.584073

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

An efficient one-pot condensation has been developed for the synthesis of polyhydroquinolines via a four component coupling reaction of aldehyde, dimedone, ethyl acetoacetate, and ammonium acetate under catalyst and solvent-free conditions. Non-hazardous experiment procedure, operational simplicity, mild reaction conditions, and the compatibility with various functional groups represent the advantages of the present method.

【 授权许可】

Unknown