Weak inter­actions in the crystal structures of two indole derivatives

Acta Crystallographica Section E: Crystallographic Communications

Kerr, J.R.²  Trembleau, L.²  Wardell, J.L.²  Storey, J.M.D.²  Harrison, W.T.A.³ 

[1] ãDepartment of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, Scotland;Fundaço Oswaldo Cruz, Instituto de Tecnologia em Fármacos-Far Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil

关键词: CRYSTAL STRUCTURE;    INDOLE;    N-H...O HYDROGEN BONDS;    INVERSION DIMERS;    WEAK INTERACTIONS;   

DOI  :  10.1107/S2056989016008616

学科分类：数学（综合）

来源: International Union of Crystallography

【 摘 要 】

We describe the syntheses and crystal structures of two indole derivatives, namely a second monoclinic polymorph of ethyl 5-chloro-1H-indole-2-carboxyl­ate C11H10ClNO2, (I), and ethyl 5-chloro-3-iodo-1H-indole-2-carboxyl­ate, C11H9ClINO2, (II). In their crystal structures, both compounds form inversion dimers linked by pairs of N—H⋯O hydrogen bonds, which generate R22(10) loops. The dimers are linked into double chains in (I) and sheets in (II) by a variety of weak inter­actions, including π–π stacking, C—I⋯π, C—Cl—π inter­actions and I⋯Cl halogen bonds.

【 授权许可】

CC BY