ОСОБЕННОСТИ ЛИПИДНОГО ОБМЕНА У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 1-ГО ТИПА С НЕУДОВЛЕТВОРИТЕЛЬНЫМ ГЛИКЕМИЧЕСКИМ КОНТРОЛЕМ С ДИАБЕТИЧЕСКИМИ МИКРОАНГИОПАТИЯМИ И БЕЗ НИХ

Acta Biomedica Scientifica

Е. В. Чугунова¹  В. С. Съемщиков²  Л. Ю. Хамнуева² 

[1] ГБУЗ «Иркутская ордена «Знак Почёта» областная клиническая больница»;ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России

关键词: сахарный диабет;    дислипидемия;    холестерин;    ЛПВП;    ЛПНП;    ЛПОНП;    триглицериды;    холестерин не-ЛПВП;   

DOI  :  10.12737/23790

学科分类：自然科学（综合）

来源: Scientific entre for Family Health and Human Reproduction Problems

【 摘 要 】

Hyperglycemia and dyslipidemia are common metabolic abnormalities in adults with type 1 diabetes mellitus (T1DM) and both increase cardiovascular disease risk. Normalization of lipid metabolism is a mandatory element in prevention of diabetic micro- and macroangiopathies in patients with T1DM and it is directly related to improvement of health outcome. We aimed to investigate serum lipid profiles in patients with T1DM and poor glycemic control. Among observed patients with T1DM, 76 % were classified as having dyslipidemia, dyslipidemia rate was higher in patients with diabetic microangiopathies. Patients with T1DM and microvascular complications, arterial hypertension (AH) and the level of glycated hemoglobin (HbA1c) > 8 % had significantly higher levels of total cholesterol (TC), very low density lipoproteins (VLDL), triglycerides (TG) and non-high density lipoproteins (non-HDL). Therefore, management of patients with T1DM at the outpatient stage requires a strict control of lipid metabolism.

【 授权许可】

CC BY