Carotid artery stenting in a single center, single operator, single type of device and 15 years of follow-up

CVIR Endovascular

Victoria Mayoral Campos¹  Ignacio de Blas Giral¹  Marí¹  Cristina Pé²  s Guirola Ó³  ñ³  rtiz⁴  ez⁴  rez Lá⁵  Miguel Á⁶  José⁶  a José⁶  Gimeno Peribá⁷  ngel de Gregorio Ariza⁷  André⁷  Carolina Serrano⁸  Carlos Tejero Juste⁸  zaro⁸ 

[1] GITMI (Grupo de InvestigacióServicio de NeurologíServicio de Radiología intervencionista, Hospital Clía, Hospital Clín en Tecnicas de Minima Invasión) del Gobierno de Aragon, Zaragoza, Spain;nico Universitario Lozano Blesa, Zaragoza, Spain

关键词: Neurointervention;    Endovascular treatment;    Carotid stenting;    Revascularization;    Carotid artery;    Carotid artery stenosis;    Stroke;    Long-term follow-up;   

DOI  :  10.1186/s42155-018-0008-2

学科分类：放射科、核医学、医学影像

来源: Springer

【 摘 要 】

Revascularization with carotid stent (CAS) is considered the therapeutic alternative to endarterectomy (CEA). However, its role compared to CEA remains questioned, mainly due of the heterogeneity of long-term results. The objective of this study was to report the efficacy and durability of CAS in terms of stroke prevention in a “real world experience”. This was a single-center retrospective analysis of 344 patients treated with CAS between January 2001 and December 2015. The primary outcome of the trial was stroke, myocardial infarction, or death during a periprocedural period or any stroke event over a 15-year follow-up. The secondary aim was to identify risk factors for 30-day complications, long-term neurological complications, and intra-stent restenosis. The primary composite end point (any stroke, myocardial infarction, or death during the periprocedural period) was 2.3%. The use of an EPD was protective against major complications. Long-term follow-up was achieved in 294 patients (85,5%) with a median of 50 months (range 0-155 months). Fifty-six (16,3%) died within this period, most commonly of nonvascular causes (4 patients had stroke-related deaths). During the follow-up period, 8 strokes and 3 TIAs were diagnosed (3.2%). ISR determined by sequential ultrasound was assessed in 4.4% of the patients and remained asymptomatic in all but 2 patients (0.6%). All patients with restenosis underwent revascularization with balloon angioplasty. The long-term follow-up results of our study validate CAS as a safe and durable procedure with which to prevent ipsilateral stroke, with an acceptable rate of restenosis, recurrence and mortality.

【 授权许可】

CC BY