Elucidating risk factors for oral leukoplakia affecting gingivae in Japanese subjects:

Translational Research in Oral Oncology

ToruNagao¹ 

关键词: Leukoplakia;    gingiva;    metal allergy;    dysplasia;    malignant transformation;   

DOI  :  10.1177/2057178X16654704

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Background:Clinicopathological studies have revealed some distinct anatomical variations in the clinical presentation of oral leukoplakia (OL). Screening studies have shown that gingival leukoplakia (GL) to be more common among the Japanese.Objective:A hospital-based case-control study was undertaken among patients diagnosed with OL to compare clinico-pathological data between GL and OL affecting other sites (n-GL).Methods:One hundred fifty-one subjects attending four city hospitals in Japan diagnosed with OL were recruited to this study. OL was diagnosed by World Health Organization criteria. They were interviewed for risk factors, clinical presentations were charted and investigated by patch testing for allergy to dental materials and by biopsy for dysplasia.Results:Eighty-eight with GL and 63 with n-GL were included in the study. GL lesions were predominantly white (93%) though n-GL leukoplakia had red (speckled) foci in 26%. Eighty percent of GL were seen in association with prosthesis or restorations...

【 授权许可】

CC BY