JNCI Cancer Spectrum | |
The Association Between Dietary Quality and Overall and Cancer-Specific Mortality Among Cancer Survivors, NHANES III | |
Sonawane, Kalyani1  Deshmukh, Ashish A1  Chiao, Elizabeth Y2  Shirvani, Shervin M3  Likhacheva, Anna3  Chhatwal, Jagpreet4  | |
[1] Department of Health Services Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, FL;Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX;Department of Radiation Oncology, Banner MD Anderson Cancer Center, Gilbert, AZ;Massachusetts General Hospital Institute for Technology Assessment, Harvard Medical School, Boston, MA | |
关键词: cancer; cancer death rate; cancer survivors; mortality; healthy diet; | |
DOI : 10.1093/jncics/pky022 | |
学科分类:肿瘤学 | |
来源: Oxford University Press | |
【 摘 要 】
Given the recent emphasis on the totality of the diet by national guidelines, we examined the relationship between the quality of diet and overall and cancer-specific mortality among cancer survivors. From the Third National Health and Nutrition Examination Survey (NHANES III), 1191 participants diagnosed with cancer were identified. Healthy Eating Index (HEI) scores were utilized; higher HEI score indicated better adherence to dietary recommendations. During a median follow-up of 17.2 years, a total of 607 cancer-specific deaths occurred. A high-quality diet (highest-quartile HEI score) was associated with decreased risk of overall (hazard ratio [HR] = 0.59, 95% confidence interval [CI] = 0.45 to 0.77) and cancer-specific (HR = 0.35, 95% CI = 0.19 to 0.63) mortality when compared with a poor-quality diet (lowest-quartile HEI score). Among individual dietary components, the highest-quartile score for saturated fat intake was associated decreased cancer-specific mortality (HR = 0.55, 95% CI = 0.36 to 0.86). Our results highlight the importance of a “total diet” approach to improving survival among cancer patients.
【 授权许可】
CC BY-NC-ND
【 预 览 】
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RO201904029641688ZK.pdf | 687KB | download |