A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial)

BMC Rheumatology

Andrew D. Dick¹  Michael W. Beresford²  Ashley P. Jones²  Helen Hickey²  Andrew McKay³  Richard Lee³  Ben Hardwick³  Catherine Guly⁴  Athimalaipet V. Ramanan⁵ 

[1]Bristol Medical School, University of Bristol, Bristol, UK

[2]Bristol Eye Hospital, Bristol, UK

[3]Clinical Trials Research Centre, Department of Biostatistics, University of Liverpool, Liverpool, UK

[4]School of Clinical Sciences, University of Bristol, UCL Institute of Ophthalmology and National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, Bristol, UK

[5]University Hospitals Bristol NHS Foundation Trust &

关键词: Juvenile Idiopathic Arthritis;    Uveitis;    Ophthalmology;    Rheumatology;    Paediatric;    Tocilizumab;    Methotrexate;    Safety;   

DOI  :  10.1186/s41927-018-0010-2

学科分类：内科医学

来源: BioMed Central

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