Expression and Localization of Cathepsins B, D, and G in Two Cancer Stem Cell Subpopulations in Moderately Differentiated Oral Tongue Squamous Cell Carcinoma

Frontiers in Medicine

Therese Featherston¹ 

关键词: oral tongue;    squamous cell carcinoma;    cancer;    cathepsin;    renin–;    angiotensin system;    cancer stem cells;    oral cavity;    head and neck;   

DOI  :  10.3389/fmed.2017.00100

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

AimWe have previously demonstrated the putative presence of two cancer stem cell (CSC) subpopulations within moderately differentiated oral tongue squamous cell carcinoma (MDOTSCC), which express components of the renin–angiotensin system (RAS). In this study, we investigated the expression and localization of cathepsins B, D, and G in relation to these CSC subpopulations within MDOTSCC.

【 授权许可】

CC BY