Investigation on the Factors Affecting Cronobacter sakazakii Contamination Levels in Reconstituted Powdered Infant Formula

Frontiers in Pediatrics

Julio Parra-Flores¹ 

关键词: Cronobacter spp;    hypothetical dose;    powdered infant formula;    contamination levels;    infants;   

DOI  :  10.3389/fped.2015.00072

学科分类：儿科学

来源: Frontiers

【 摘 要 】

IntroductionCertain strains of Cronobacter sakazakii can cause serious invasive infections in children, mainly those <2 months old and fed with powdered infant formula (PIF). The infectious dose of C. sakazakii is unknown but evidence suggests that it is approximately 1000 colony forming units (CFU). PIF is currently considered safe if its end-product C. sakazakii level is <1 CFU/g. In this study, we determined the lag time, generation time (GT), and growth rate of five pooled C. sakazakii isolates to evaluate the factors affecting contamination levels in reconstituted PIF.

【 授权许可】

CC BY