Spatiotemporal Permutation Entropy as a Measure for Complexity of Cardiac Arrhythmia

Frontiers in Physics

Berg, Sebastian¹  Schlemmer, Alexander²  Parlitz, Ulrich²  Lilienkamp, Thomas³  Luther, Stefan⁴ 

[1] Institute for Nonlinear Dynamics, Georg-August-UniversitäResearch Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Germany;t Göttingen, Germany

关键词: permutation entropy;    cardiac arrhythmia;    Fenton-Karma simulation;    Complexity;    excitable media;    Phase singularities;   

DOI  :  10.3389/fphy.2018.00039

学科分类：物理（综合）

来源: Frontiers

【 摘 要 】

Permutation entropy (PE) is a robust quantity for measuring the complexity of time series. In the cardiac community it is predominantly used in the context of electrocardiogram (ECG) signal analysis for diagnoses and predictions with a major application found in heart rate variability parameters. In this article we are combining spatial and temporal PE to form a spatiotemporal PE that captures both, complexity of spatial structures and temporal complexity at the same time. We demonstrate that the spatiotemporal PE (STPE) quantifies complexity using two datasets from simulated cardiac arrhythmia and compare it to phase singularity analysis and spatial PE (SPE). These datasets simulate ventricular fibrillation (VF) on a two-dimensional and a three-dimensional medium using the Fenton-Karma model. We show that SPE and STPE are robust against noise and demonstrate its usefulness for extracting complexity features at different spatial scales.

【 授权许可】

CC BY