Primary renal angiosarcoma: A case report and literature review

Precision Radiation Oncology

Hong Zhang¹  Shuang Wang²  Shun dong Dai³  Xiao li Li³  Jin Guo⁴  Xin Tian⁵ 

[1]Department of Colorectal Surgery Shengjing Hospital of China Medical University Shenyang Liaoning China

[2]Department of Pathology Shenyang Red Cross Hospital Shenyang Liaoning China

[3]Department of Pathology The First Affiliated Hospital and College of Basic Medical Sciences China Medical University Shenyang Liaoning China

[4]Department of Toxicological Pathology Safety Evaluation Center, Shenyang Research Institute of Chemical Industry Shenyang Liaoning China

[5]Molecular Oncology Laboratory of Cancer Research Institute The First Affiliated Hospital of China Medical University Shenyang Liaoning China

关键词: angiosarcoma;    angiosarcoma of the kidney;    primary renal angiosarcoma;   

DOI  :  10.1002/pro6.51

学科分类：医学（综合）

来源: Wiley

【 摘 要 】

Kidney angiosarcomas usually metastasize from the skin, soft tissue, or visceral primary lesions, whereas primary renal angiosarcomas are rare. We report a case of primary renal angiosarcoma with morphological features similar to those of anastomosis hemangioma. Microscopically, there were multiple irregular anastomosing vascular spaces or channel‐like labyrinthine structures, and the tumor cells were positive for CD31, CD34, FLI‐1, PAX8, and vimentin; focally positive for factor VIII, CD10, and Ki‐67 (approximately 5%); and uniformly‐negative for CK, S‐100, and Melan‐A. The diagnosis of angiosarcoma depends on morphological and immunohistochemical examinations.

【 授权许可】

CC BY-NC-ND