Getting Lost Behavior in Patients with Mild Alzheimer’s Disease: A Cognitive and Anatomical Model

Frontiers in Medicine

Chathuri Yatawara¹ 

关键词: Alzheimer’;    s disease;    getting lost;    wayfinding;    medial temporal lobe;    top-down modulation;   

DOI  :  10.3389/fmed.2017.00201

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

BackgroundGetting lost behavior (GLB) in the elderly is believed to involve poor top-down modulation of visuospatial processing, by impaired executive functions. However, since healthy elderly and elderly with Alzheimer’s disease (AD) experience a different pattern of cognitive decline, it remains unclear whether this hypothesis can explain GLB in dementia.

【 授权许可】

CC BY