期刊论文详细信息
Genomics Insights
Comparative Genomics of Bacillus species and its Relevance in Industrial Microbiology:
ArchanaSharma1 
关键词: Bacillus;    genome sequencing;    comparative genomics;    sequencing platforms;    industrial enzymes;   
DOI  :  10.4137/GEI.S12732
学科分类:生物科学(综合)
来源: Sage Journals
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【 摘 要 】

With the advent of high throughput sequencing platforms and relevant analytical tools, the rate of microbial genome sequencing has accelerated which has in turn led to better understanding of microbial molecular biology and genetics. The complete genome sequences of important industrial organisms provide opportunities for human health, industry, and the environment. Bacillus species are the dominant workhorses in industrial fermentations. Today, genome sequences of several Bacillus species are available, and comparative genomics of this genus helps in understanding their physiology, biochemistry, and genetics. The genomes of these bacterial species are the sources of many industrially important enzymes and antibiotics and, therefore, provide an opportunity to tailor enzymes with desired properties to suit a wide range of applications. A comparative account of strengths and weaknesses of the different sequencing platforms are also highlighted in the review.

【 授权许可】

CC BY   

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