Modular Endoprosthesis for Mandibular Reconstruction — A Thematic Research Study at the National Dental Centre Singapore:

Proceedings of Singapore Healthcare

Bee TinGoh¹ 

关键词: Jaw;    Prosthesis;    Tissue engineering;   

DOI  :  10.1177/201010581202100103

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Introduction:A thematic research project was undertaken by the National Dental Centre Singapore to study the feasibility of using a novel modular endoprosthesis for reconstruction of the mandible. Successful application of this technique potentially eliminates the need for a donor site.Methods:Three sub-projects done in a monkey model are presented. In the first two sub-projects, a titanium modular endoprosthesis was inserted in surgically created defects for reconstruction of the ascending ramus and condyle; and body of the mandible respectively. In the third sub-project, a polycaprolactone scaffold with calcium phosphate (CaP) surface coating modular endoprosthesis was used for reconstruction of the body of the mandible. The animals were sacrificed at three to six months. Microcomputed tomographic and histologic analyses were done.Results:At the time of sacrifice, signs of infection were present in a few animals treated either with the titanium or the polycaprolactone endoprosthesis for replacement of t...

【 授权许可】

CC BY