ПОРАЖЕНИЕ СЕРДЦА ПРИ СИНДРОМЕ ЧАРДЖА - СТРОССА

Acta Biomedica Scientifica

Е. С. Енисеева¹  О. В. Каня²  А. А. Стефаненкова²  Г. П. Гуртовая³ 

[1] ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава России;ГБУЗ Иркутское областное патологоанатомическое бюро;ФГБОУ ВО «Иркутский государственный медицинский университет» Минздрава России

关键词: синдром Чарджа - Стросса;    эозинофилия;    коронариит;    кардиомиопатия;   

DOI  :  10.12737/23843

学科分类：自然科学（综合）

来源: Scientific entre for Family Health and Human Reproduction Problems

【 摘 要 】

Cardiac involvement is the most important prognostic factor in eosinophilic granulomatosis with polyangiitis (Churg - Strauss syndrome). We report a case of Churg - Strauss syndrome in 65-year-old women masquerading as a non-ST elevation myocardial infarction. She had chest discomfort, dyspnea and ST depression, high troponin level and so myocardial infarction was diagnosed. She had had asthma for 4 years but had no eosinophilia in peripheral blood and lesions in the lungs at the time of the first hospitalization. Her skin was clean without rashes. 3 months later she was hospitalized again having pulmonary infiltrates. Laboratory tests revealed that eosinophil was significantly increased. Cardiac involvement in a pathological process led to death. Histological examination of heart and lungs showed necrotic coronary vasculitis, granulomas and perivascular eosinophilic infiltrates in myocardium, endocardium, pericardium and pulmonary eosinophilic infiltrates.

【 授权许可】

CC BY