期刊论文详细信息
| Pulmonary Circulation | |
| Epigenetic Modifications: Basic Mechanisms and Role in Cardiovascular Disease (2013 Grover Conference Series): | |
| JosephLoscalzo1 | |
| 关键词: methylation; histone; noncoding RNAs; atherosclerosis; homocysteine; pulmonary hypertension; | |
| DOI : 10.1086/675979 | |
| 学科分类：医学（综合） | |
| 来源: Sage Journals | |
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【 摘 要 】
Epigenetics refers to heritable traits that are not a consequence of DNA sequence. Three classes of epigenetic regulation exist: DNA methylation, histone modification, and noncoding RNA action. In the cardiovascular system, epigenetic regulation affects development, differentiation, and disease propensity or expression. Defining the determinants of epigenetic regulation offers opportunities for novel strategies for disease prevention and treatment.
【 授权许可】
CC BY
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201904027541563ZK.pdf | 1585KB |  download |
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