Состояние портопечёночной гемодинамики при печёночной недостаточности у больных деструктивным панкреатитом

Acta Biomedica Scientifica

Д. И. Решетников²  А. Н. Плеханов³ 

[1] НУЗ «Отделенческая клиническая больница на ст. Улан-Удэ ОАО «РЖД»;ФГБНУ «Иркутский научный центр хирургии и травматологии»;ФГБОУ ВПО «Бурятский государственный университет»

关键词: панкреатит;    печеночная недостаточность;    гемодинамика;    диагностика;   

DOI  :  10.12737/22971

学科分类：自然科学（综合）

来源: Scientific entre for Family Health and Human Reproduction Problems

【 摘 要 】

Extraorgan complications of acute destructive pancreatitis are registered in 60-95 % of patients. Liver failure is registered in one of the four patients with pancreatic necrosis. We analyzed the results of surgical treatment of 122 patients with acute destructive pancreatitis. We studied clinical indicators of liver failure in 103 (84.4 %) patients with acute pancreatitis. The development of portal hypertension with decrease in hepatic volume perfusion is an important element in the pathogenesis of acute pancreatitis and associated liver function abnormalities. In patients with severe and moderate liver failure, the reduction of blood flow in portal vein was registered. It was caused by reduce of portal vein diameter and decrease in linear blood flow velocity. Destructive pancreatitis is accompanied by liver failure with hyperbilirubinemia, increased activity of cytolytic enzymes, incoordination in protein and carbohydrate metabolism as its common manifestations. An important factor in the pathogenesis of liver failure is a reduction of porto-hepatic hemodynamics and as a consequence - hepatic hypoperfusion.

【 授权许可】

CC BY