Histological Analysis of Early Osteolysis in Total Ankle Arthroplasty:

Foot & Ankle Orthopaedics

OliverSchipper¹ 

关键词: ankle arthritis;    ankle arthroplasty;    ankle replacement;    osteolysis;   

DOI  :  10.1177/2473011417S000075

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Category:Ankle ArthritisIntroduction/Purpose:The purpose of this study was to perform a histological comparative analysis of tibiotalar joint samples taken from areas of osteolysis adjacent to total ankle arthroplasties vs control synovial specimens to determine the reaction to and presence of polyethylene (PE) particles.Methods:A total of 57 pathology samples were identified in the osteolysis group, while 11 were identified in the control group. For each sample, hematoxylin and eosin, Oil Red O (ORO), and macrophage marker CD163-stained slides were created. Polarized light and ORO stain were used to identify PE particles. The presence of metal particles and giant cell reaction to PE particles were also scored.Results:Macrophages, PE particles, metallosis, and foreign body giant cell reaction scores were significantly higher in the osteolysis group compared with the control group. In the osteolysis group, ORO staining was positive in 93% (53/57), birefringent material was present in 96.5% (55/57), and mac...

【 授权许可】

CC BY