Decreasing Nicotine Content Reduces Subjective and Physiological Effects of Smoking:

Tobacco Use Insights

David M.Penetar¹ 

关键词: nicotine;    smoking;    subjective sensations;    physiological;   

DOI  :  10.4137/TUI.S8523

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

ObjectiveAssessment of the subjective and physiological effects of smoking cigarettes with different machine-smoked nicotine yields.MethodsEight volunteers rated the characteristics of cigarettes with varying levels of nicotine (Quest®). At 30 minute intervals, participants smoked one of three different Quest® brand cigarettes in a counterbalanced order (reported machine-smoked nicotine yield: 0.6 mg, 0.3 mg, or 0.05 mg). Smoking satisfaction and sensations were measured on a cigarette evaluation questionnaire. A mood questionnaire measured self-reported subjective changes in ‘happy’, ‘stimulated’, ‘anxious’, ‘desire to smoke’, and ‘desire not to smoke’. Heart rate and skin temperature were recorded continuously.ResultsAs nicotine yield decreased, cigarettes produced smaller changes in subjective ratings on the evaluation questionnaire with the placebo nicotine cigarette always rated lower or less potent than the other two cigarettes evaluated. Heart rate was significantly increased by the reduced nicotin...

【 授权许可】

CC BY