Frontiers in Medicine | |
Ulcerative Gastritis and Esophagitis in Two Children with Sarcina ventriculi Infection | |
Tim G. J. de Meij1  | |
关键词: esophagitis; children; microbiota; IS-pro; Sarcina ventriculi; gastritis; | |
DOI : 10.3389/fmed.2017.00145 | |
学科分类:医学(综合) | |
来源: Frontiers | |
【 摘 要 】
Sarcina ventriculi is a Gram-positive, obligate anaerobic coccus, with a characteristic morphology. Only 22 cases of human infections by this microorganism, including 7 in children, have been reported in literature so far. Affected subjects usually present with abdominal pain, nausea, vomiting, and delayed gastric emptying. However, life-threatening complications, like emphysematous gastritis and gastric perforation have also been described. Gastroparesis and gastric outlet obstruction have been considered as a potential etiologic factor. All pediatric cases described thus far presented with concomitant gastrointestinal pathology, such as Helicobacter pylori gastritis, celiac disease, infection with Giardia lamblia or Candida spp. Here, we report two children with S. ventriculi infection, in whom the diagnosis was established by typical histological findings in mucosal biopsies. The first child presented with hematemesis due to ulcerative esophagitis and gastritis, the second child with a history of esophageal stricture had ulcerative gastritis. Confirmation of S. ventriculi infection is feasible by molecular microbiota detection methods, since this microorganism cannot be detected by classical culture techniques. Prompt treatment with antibiotics could prevent life-threatening complications.
【 授权许可】
CC BY
【 预 览 】
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RO201904026131471ZK.pdf | 1262KB | download |