Non-response to Interleukin-1 Antagonist Canakinumab in Two Patients with Refractory Pyoderma Gangrenosum and Hidradenitis Suppurativa

The Journal of Clinical and Aesthetic Dermatology

Natalie Z. Sun¹ 

关键词: Pyoderma gangrenosum;    hidradenitis suppurativa;    acne inversa;    PASH;    anti-IL-1 therapy;    anti-TNF therapy;    canakinumab;   

DOI  :  

学科分类：医学（综合）

来源: Matrix Medical Communications, LLC

【 摘 要 】

Pyoderma gangrenosum and hidradenitis suppurativa are skin conditions characterized by an intense neutrophil-mediated inflammatory response that is often difficult to effectively treat. Successful use of interleukin (IL)-1β inhibition using canakinumab ...

【 授权许可】

Unknown