Addressing the challenges of phenotyping pediatric pulmonary vascular disease:

Pulmonary Circulation

Kara N.Goss¹ 

关键词: childhood;    pulmonary hypertension;    registry studies;    long-term outcomes;   

DOI  :  10.1086/689750

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Pediatric pulmonary vascular disease (PVD) and pulmonary hypertension (PH) represent phenotypically and pathophysiologically diverse disease categories, contributing substantial morbidity and mortality to a complex array of pediatric conditions. Here, we review the multifactorial nature of pediatric PVD, with an emphasis on improved recognition, phenotyping, and endotyping strategies for pediatric PH. Novel tailored approaches to diagnosis and treatment in pediatric PVD, as well as the implications for long-term outcomes, are highlighted.

【 授权许可】

CC BY