From weight loss to weight gain: appetite changes in major depressive disorder as a mirror into brain-environment interactions

Frontiers in Psychology

Gregory J. Privitera¹ 

关键词: dopaminergic pathways;    mood;    depression;    reward system;    atypical depression;    sociocultural shifts;   

DOI  :  10.3389/fpsyg.2013.00873

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

In recent decades, there has been a profound shift in the appetitive characteristics of depression. For early measures of depression, such as the Hamilton Rating Scale for Depression (HRSD; Hamilton, 1960), the key appetitive characteristic of depression was weight loss. In the 1950s and 60s, reduced appetite was considered a key feature even in mild depression and it was noted that in moderate depression the desire for food may almost totally disappear (Beck, 1967); those suffering with severe depression may almost have to force themselves to eat (Schuyler, 1974; Polivy and Herman, 1976). Zung, another pioneer of depression measurement, found that even the individual designated as the significant “other” associated loss of appetite as symptomatic of depression in the patient (Zung et al., 1974). No assessment for increased appetite, food intake, or weight gain was assessed in the HRSD. In these early reports, people with depression who overate or gained weight were diagnosed with “atypical depression” and were treated differently than those with more “typical” depression characterized by weight loss.

【 授权许可】

CC BY