Patient reported adverse events among epileptic patients taking antiepileptic drugs:

SAGE Open Medicine

Mohammed BisetAyalew¹ 

关键词: Adverse event;    side effect;    epilepsy;    antiepileptic drug;    seizure;   

DOI  :  10.1177/2050312118772471

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objective:The aim of this study was to assess patient reported adverse events and associated factors among epileptic patients taking antiepileptic drugs on follow-up at University of Gondar Referral Hospital.Methods:Cross-sectional study was done on 354 adult epileptic patients. Patients who were on antiepileptic drugs for epilepsy treatment for less than a year, those who were below 18 years old, patients with incomplete information on the chart and those who were involuntary or uncooperative were excluded from the study. Data were entered in to SPSS version 20.0 for analysis. Bivariate and multivariate binary logistic regression analysis was done to see factors associated with antiepileptic drugs adverse effect. Level of statistical significance was declared at p ≤ 0.05.Result:Generalized tonic clonic seizure was the most common (86.2%) type of epilepsy. A total of 79 adverse events were reported. The most frequently encountered adverse events were fatigue (5.08%), gastrointestinal disturbance (4.24%) a...

【 授权许可】

CC BY