Some Considerations about the Value Based Pricing in Oncology: An Analysis on Metastatic First Line Medicinal Products:

Global & Regional Health Technology Assessment

FedericoSpandonaro¹ 

关键词: Italy;    Mean;    Median;    Oncology;    Pricing;    Survival;   

DOI  :  10.5301/GRHTA.5000218

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

IntroductionIn recent years public health systems have faced the challenge of ensuring sustainable costs for innovative medicinal products. The aim of this study is to analyse pricing behaviour applied in the Italian oncology sector.MethodsThe study examined all new oncologic compounds that are reimbursed in Italy, for utilization in the first-line metastatic setting. A regression model was developed to analyse the relation between drug price, clinical benefit, market potential and the year in which reimbursement was granted in Italy. The clinical benefit was measured by increment in Overall Survival respect to standard of care; two different metrics were considered, namely median and mean.ResultsThe analysis revealed a strong correlation between price and clinical benefit and a weak negative correlation between prices and volumes; no time trends were observed in reimbursement price reduction. As regards pricing, the Italian Medicines Agency seems to have maintained basically consistent reference levels o...

【 授权许可】

CC BY