Impatto Economico Dei Regimi Semplificati a Base di Raltegravir Nel Trattamento di Mantenimento Dei Pazienti HIV-1 Infetti in Soppressione Virologica:

Global & Regional Health Technology Assessment

RobertoRavasio¹ 

关键词: Antiretroviral therapy;    Cost;    Dual-therapy;    Raltegravir;   

DOI  :  10.5301/grhta.5000266

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Budget impact analysis in the maintenance raltegravir-containing regimen in virologically suppressed HIV infected patientsBackgroundA one-year cost analysis was conducted to estimate the impact from the perspective of the Italian National Health Service (NHS) of nevirapine or etravirine or rilpivirine plus raltegravir administration as maintenance antiretroviral therapy in virologically suppressed HIV-1 infected patients.MethodsPatient data were retrieved from the electronic medical record system in use (year 2016) in a reference HIV centre in South Italy. The analysis considered patients with long-term (more than 1 year) virological suppression (HIV-1 RNA <50 copies/mL) on Highly Active Antiretroviral Therapy (HAART) and no prior exposure to integrase inhibitors (INIs). To estimate the total HAART expenditure, we calculated the annual treatment cost for each enrolled patient. Subsequently, to estimate the dual therapy hypothetical expenditure, we assumed to treat the same patients with nevirapine or rilp...

【 授权许可】

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