A brief procedure for big data analysis of gene expression

Animal Models and Experimental Medicine

Wenji Wang¹  Kewei Wang²  Mang Li³ 

[1] Center for Endemic Disease Control Chinese Center for Disease Control and Prevention Harbin China;Institute of Cell Biotechnology China and Russia Medical Research Center HarbinChina;Key Laboratory of Etiology and Epidemiology National Health and Family Planning Commission of the People's Republic of China Harbin China

关键词: big data analysis;    cluster analysis;    microarray;    PCA analysis;    regression model;   

DOI  :  10.1002/ame2.12028

学科分类：医学（综合）

来源: Wiley

【 摘 要 】

There are a lot of biological and experimental data from genomics, proteomics, drug screening, medicinal chemistry, etc. A large amount of data must be analyzed by special methods of statistics, bioinformatics, and computer science. Big data analysis is an effective way to build scientific hypothesis and explore internal mechanism. Here, gene expression is taken as an example to illustrate the basic procedure of the big data analysis.

【 授权许可】

CC BY