The role of bone marrow edema on autologous matrix induced chondrogenesis for the treatment of osteochondral lesions of the talus:

Foot & Ankle Orthopaedics

RiccardoD’Ambrosi¹ 

关键词: osteochondral talar lesions;    autologous matrix induced chondrogenesis;    bone marrow edema;    ankle arthroscopy;   

DOI  :  10.1177/2473011417S000151

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Category:Ankle, Arthroscopy, Basic Sciences/BiologicsIntroduction/Purpose:to assess the functional and radiological outcomes after AT-AMIC® (arthroscopic talus autologous matrix induced chondrogenesis) in 2 groups: patients with and without bone marrow edema (BME).Methods:Thirty-seven patients of which 24 without edema (GNE) and 13 with edema (GE) were evaluated. All patients were treated with AT-AMIC® repair for osteochondral talar lesion. MRI and CT-scan evaluations, as well as clinical evaluations measured by the VAS score for pain, AOFAS and SF-12 were performed preoperatively (T0) and at 6 (T1), 12 (T2), and 24 (T3) months postoperatively.Results:GNE consisted of 24 patients while GE consisted of 13 patients. In both groups we found a significant difference for clinical and radiological parameters with ANOVA for repeated measures through four time points(p<0.001). In GNE, AOFAS improved significantly at each follow-up(p<0.05); while CT and MRI showed a significant decrease between T1 and T2 and T2 an...

【 授权许可】

CC BY