Negative Affectivity, Depression, and Resting Heart Rate Variability (HRV) as Possible Moderators of Endogenous Pain Modulation in Functional Somatic Syndromes

Frontiers in Psychology

Maaike Van Den Houte¹ 

关键词: endogenous pain modulation;    conditioned pain modulation;    counter-irritation;    fibromyalgia;    chronic fatigue syndrome;    heart rate variability;    negative affectivity;    depression;   

DOI  :  10.3389/fpsyg.2018.00275

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

Background: Several studies have shown that patients with functional somatic syndromes (FSS) have, on average, deficient endogenous pain modulation (EPM), as well as elevated levels of negative affectivity (NA) and high comorbidity with depression and reduced resting heart rate variability (HRV) compared to healthy controls (HC). The goals of this study were (1) to replicate these findings and (2) to investigate the moderating role of NA, depression, and resting HRV in EPM efficiency within a patient group with fibromyalgia and/or chronic fatigue syndrome (CFS). Resting HRV was quantified as the root mean square of successive differences between inter-beat intervals (RMSSD) in rest, a vagally mediated time domain measure of HRV.

【 授权许可】

CC BY