Pantoprazole Does not Affect Serum Trough Levels of Tacrolimus and Everolimus in Liver Transplant Recipients

Frontiers in Medicine

Sebastian C. B. Bremer¹ 

关键词: immunosuppressive drugs;    pantoprazole;    serum trough levels;    liver transplant recipients;    tacrolimus;    everolimus;   

DOI  :  10.3389/fmed.2018.00320

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

Background: Liver transplant recipients are frequently treated with proton pump inhibitors. Drug interactions have been described especially with respect to omeprazole. Due to the lower binding capacity of pantoprazole to CYP2C19 this drug became preferred and became the most used proton pump inhibitor in Germany. The data on the influence of pantoprazole on immunosuppressive drugs in liver transplant recipients a very scarce.

【 授权许可】

CC BY