The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis

Frontiers in Medicine

Carl K. Orr¹ 

关键词: synovium;    inflammatory biomarkers;    disease activity;    rheumatoid arthritis;    synovial biopsy;   

DOI  :  10.3389/fmed.2018.00185

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

Introduction: Identifying and quantifying inflammatory disease activity in rheumatoid arthritis remains a challenge. Many studies have suggested that a large proportion of patients may have active inflammation, but normal inflammatory markers. Although various disease activity scores have been validated, most rely to a large degree on biomarkers such as CRP and ESR. In this study, we examine the utility and limitations of these biomarkers, as well as the DAS28-CRP in appraising disease activity in RA.

【 授权许可】

CC BY