Respiratory Microbiome of New-Born Infants

Frontiers in Pediatrics

David J. Gallacher¹ 

关键词: bronchopulmonary dysplasia;    chronic lung disease;    prematurity;    microbiome;    lung;    colonization;    16S RNA gene;    neonate;   

DOI  :  10.3389/fped.2016.00010

学科分类：儿科学

来源: Frontiers

【 摘 要 】

The respiratory tract, once believed to be sterile, harbors diverse bacterial communities. The role of microorganisms within health and disease is slowly being unraveled. Evidence points to the neonatal period as a critical time for establishing stable bacterial communities and influencing immune responses important for long-term respiratory health. This review summarizes the evidence of early airway and lung bacterial colonization and the role the microbiome has on respiratory health in the short and long term. The challenges of neonatal respiratory microbiome studies and future research directions are also discussed.

【 授权许可】

CC BY