Hemodiafiltration Treatment for Severe Valproic Acid Intoxication: Case Report and Updated Systematic Literature Review

Frontiers in Medicine

Tobias Tichelbäcker¹ 

关键词: hemodialysis;    intoxication;    valproic acid;    extracorporeal treatment;    hemodiafiltration;   

DOI  :  10.3389/fmed.2018.00224

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

Background: Valproic acid (VPA) has been approved for the treatment of seizure disorders. It is also commonly used in psychiatric disorders, such as schizophrenia spectrum disorders. With increasing administration, reports of intoxications are more frequently reported. The most common findings of VPA intoxication are central nervous system depression, respiratory depression, hypotension, metabolic acidosis, and elevated lactate, among others.

【 授权许可】

CC BY